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Research

Published Research - Pre Clinical

Lobo D.S., Souza R.P., Tong R.P., Casey D.M., Hodgins D.C., Smith G.J., Williams R.J., Schopflocher D.P., Wood R.T., el-Guebaly N. & Kennedy J.L. (2010). Association of functional variants in the dopamine D-2 like receptors with risk for gambling behavior in healthy Caucasian subjects. Biological Psychiatry, 85(1), 33-37.

Lobo, D.S.S. & Kennedy, J.L. (2009). Genetic aspects of pathological gambling: A complex disorder with shared genetic vulnerabilities. Addiction,104(9),1454-1465.

Lobo, D.S. & Kennedy, J.L. (2006). The genetics of gambling and behavioural addictions. CNS Spectr, 11(12), 931-939.

da Silva Lobo, D.S.,Vallada H.P., Knight, J., Martins, S.S., Tavares, H., Gentil, V. & Kennedy, J.L. (2007). Dopamine genes and pathological gambling in discordant sib-pairs. Journal of Gambling Studies, 421-433.

Kennedy, J. & Turner, N.E. (2009). Candidate gene studies in problem gambling. Submitted to the Ontario Problem Gambling Research Centre.

Kennedy, J.L. & Lobo, D.S.S. (2010). Investigation of selected signalling system genes in pathological gambling: Final Report. Submitted to the Ontario Problem Gambling Research Centre.

Malat, J., Collins, J., Dhayanandhan, B., Carullo, F. & Turner, N.E. (2010).Addictive behaviors in comorbid addiction and mental illness: Preliminary results from a self-report questionnaire. Journal of Addiction Medicine 4, 38-46

Quilty, L.C., Mehra, P., Toneatto, T. & Bagby M. (2010). Impulsivity and pathological gambling across depressive versus bipolar disorders. International Gambling Studies, 10(1), 81-90. 

Stewart, S. H., Zack, M., Collins, P., Klein, R. M. & Fragopoulos, F. (2008). Sub-typing pathological gamblers on the basis of affective motivations for gambling: Relations to gambling problems, drinking problems, and affective motivations for drinking. Psychology of Addictive Behaviors, 22, 257-268.

Toneatto, T., Turner, N.E., Zack, M., Farvolden, P. & Bagby, M. (2009). The heterogeneity of problem gambling: An analysis of gambling sub-types. Ontario Problem Gambling Research Centre.

Tremblay, A.M., Desmond, R.C., Poulos, C.X. & Zack. M. (2010). Haloperidol modifies instrumental aspects of slot machine gambling in pathological gamblers and healthy controls. Addiction Biology. E-pub March 2010.

Vachon, D. D. & Bagby, R. M.  (2009).  Pathological Gambling Subtypes.  Psychological Assessment, 21(4), 608-615.

Steinberg L., Tremblay A.M, Zack M., Busto U.E. & Zawertailo L.A. (2011). Effects of stress and alcohol cues in men with and without gambling and alcohol use disorders. Drug and Alcohol Dependence, 119(1-2), 46-55.

Zack, M. & Poulos, C. X. (2007). A D2 antagonist enhances the rewarding and priming effects of a gambling episode in pathological gamblers. Neuropsychopharmacology 32(8), 1678-1686.  

Zack, M. (2006). What can affective neuroscience teach us about gambling? Journal of Gambling Issues, 16, 1-13.

Zack, M., Stewart, S. H., Klein, R. M., Loba, P. & Fragopoulos, F. (2005). Contingent gambling-drinking patterns and problem drinker status moderate implicit gambling-alcohol associations in problem gamblers. Journal of Gambling Studies: Special Issue on Co-Morbid Gambling and Alcohol Use Disorders, 21, 325-354.

Zack, M. & Poulos, C.X. (2009). Parallel roles for dopamine in pathological gambling and psychostimulant addiction.  Current Drug Abuse Reviews, 2(1), 11-25.

Zack, M. & Poulos, C.X. (2008). Preclinical investigation of the glutamate enhancer, Modafinil, as a potential medication for problem gamblers: Assessment of differential drug responsiveness as a function of impulsivity and boredom proneness. Submitted to the Ontario Problem Gambling Research Centre.

Zack, M. & Poulos, C.X. (2009). Effects of the atypical stimulant modafinil on a brief gambling episode in pathological gamblers with high versus low impulsivity. Journal of Psychopharmacology, 23(6), 660-71.

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